| 21/09 | | | |
 19:45 | Zrinjski – AZ | 2 1.70 | |
| 19:45 | Legia – Aston Villa | 2 1.50 | |
| 19:45 | Ferencváros – Čukarički | 1 1.25 | |
| 19:45 | Genk – Fiorentina | X2 1.36 | |
| 19:45 | HJK – PAOK | UNDER 1.85 | |
| 19:45 | Fenerbahçe – Nordsjælland | OVER 1.65 | |
| 19:45 | Ludogorets – FC Spartak Trnava | UNDER 2.10 | |
| 19:45 | LASK – Liverpool | OVER 1.44 | |
| 19:45 | Panathinaikos – Villarreal | 1X 1.53 | |
| 19:45 | Rennes – M. Haifa | OVER 1.67 | |
| 19:45 | Sheriff – Roma | 2 1.45 | |
| 19:45 | Qarabağ – Molde | X2 1.53 | |
| 22:00 | Slovan – Klaksvík | 1 1.60 | |
| 22:00 | Zorya Luhansk – Gent | 2 1.40 | |
| 22:00 | Dinamo – Astana | 1 1.25 | |
| 22:00 | Viktoria Plzeň – Ballkani | 1 1.30 | |
| 22:00 | Club Brugge – Beşiktaş | OVER 1.70 | |
| 22:00 | Lugano – Bodø/Glimt | X2 1.36 | |
| 22:00 | Olympiacos – Freiburg | 1X 1.44 | |
| 22:00 | Ajax – Marseille | OVER 1.67 | |
| 22:00 | Brighton – ΑΕΚ | 1 1.20 | |
| 22:00 | Rangers – Betis | 1X 1.40 | |
| 22:00 | Sparta Praha – Aris | 1 1.50 |
